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In breast cancer, over 40% of HR cases have PIK3CA mutations, driving overactive PI3K signaling that fuel cancer growth. Marie-Gabrielle Braun, Senior Principal Scientist & Project Leader at Genentech, uses everyday objects to explain how cancer therapies are becoming more precise in going after mutated pathways, enabling new ways to fight back while sparing healthy cells. | Genentech
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Breast cancer is one of the most common cancers in women, often caused by mutations in the PI3K pathway. One of the key mutations in this pathway is in the PIK3CA gene, which is found in about 40% of HR cases. Using everyday objects, Marie-Gabrielle Braun, Senior Principal Scientist & Project Leader at Genentech, explains how cancer therapies are becoming more precise in targeting this elusive pathway. Learn more about PIK3CA in breast cancer and watch the full video series: http://spr.ly/6188sJ
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PIK3CA is the most commonly mutated gene in ~40% of patients with HR /HER2- breast cancer. Learn more about the PIK3CA mutation, how it may affect your cancer care and questions to ask your doctor about testing for mutations. #ASCO21 https://bddy.me/2T20ydO | Novartis Cancer
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๐Ÿ’ก๐—Ÿ๐—ผ๐—ผ๐—ธ๐—ถ๐—ป๐—ด ๐—ณ๐—ผ๐—ฟ ๐—ฎ ๐—ณ๐—ฎ๐˜€๐˜, ๐—ฐ๐—ผ๐˜€๐˜-๐—ฒ๐—ณ๐—ณ๐—ฒ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐˜„๐—ฎ๐˜† ๐˜๐—ผ ๐—ฑ๐—ฒ๐˜๐—ฒ๐—ฐ๐˜ ๐—ฃ๐—œ๐—ž๐Ÿฏ๐—–๐—” & ๐—”๐—ž๐—ง๐Ÿญ ๐—บ๐˜‚๐˜๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€? Discover the ๐—จ๐—ฃ๐——๐—”๐—ง๐—˜๐—— ๐—œ๐—ฑ๐˜†๐—น๐—น๐—ฎโ„ข ๐—ฃ๐—œ๐—ž๐Ÿฏ๐—–๐—”-๐—”๐—ž๐—ง๐Ÿญ ๐— ๐˜‚๐˜๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—”๐˜€๐˜€๐—ฎ๐˜†: โœ… ๐—–๐—ผ๐—บ๐—ฝ๐—ฟ๐—ฒ๐—ต๐—ฒ๐—ป๐˜€๐—ถ๐˜ƒ๐—ฒ ๐—ฐ๐—ผ๐˜ƒ๐—ฒ๐—ฟ๐—ฎ๐—ด๐—ฒ: Detection of 13 PIK3CA mutations and 1 AKT1 mutation โœ… ๐— ๐—ถ๐—ป๐—ถ๐—บ๐—ฎ๐—น ๐˜€๐—ฎ๐—บ๐—ฝ๐—น๐—ฒ ๐—ฟ๐—ฒ๐—พ๐˜‚๐—ถ๐—ฟ๐—ฒ๐—บ๐—ฒ๐—ป๐˜๐˜€: Directly from 1 FFPE tissue section (5 - 10 µm) with hands-on time under 3 minutes โœ… ๐—˜๐—ณ๐—ณ๐—ถ๐—ฐ๐—ถ๐—ฒ๐—ป๐˜ ๐˜„๐—ผ๐—ฟ๐—ธ๐—ณ๐—น๏ฟฝ
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