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Leuco depletion, also known as leukodepletion or leukoreduction, is a medical process that involves the removal or reduction of white blood cells (leukocytes) from blood or blood products. This procedure is commonly performed during the preparation of blood for transfusions. The primary goals of leuco depletion are to reduce the risk of adverse reactions in the recipient, such as febrile non-hemolytic transfusion reactions, and to minimize the transmission of infections and immune modulation ass
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