Androgen increases homocysteine concentration by downregulating the key enzymes in homocysteine metabolism. And then Hcy promotes GCs autophagy via the mTOR signal …

Homocysteine (/ ˌhoʊmoʊˈsɪstiːn /; symbol Hcy) is a non-proteinogenic α-amino acid. It is a homologue of the amino acid cysteine, differing by an additional methylene bridge (−CH2−). It …

Apr 7, 2025 · A groundbreaking study published in the International Journal of Andrology demonstrated that men with elevated homocysteine levels had significantly lower free …

These results demonstrate regulation of the homocysteine-clearing enzyme, CBS, by testosterone and suggest the potential utility of targeting this enzyme as a chemotherapeutic strategy.

Mar 6, 2025 · Homocysteine is an amino acid that the body produces. Most people have low homocysteine levels. This is because the body breaks down the amino acid quickly into other …

3 days ago · Mauvais-Jarvis and Bhasin provide an in-depth review of testosterone’s role in maintaining cardiometabolic health, musculoskeletal integrity and energy balance, drawing on …

Jan 31, 2025 · What is homocysteine? Homocysteine (Hcy) is an amino acid. It’s a chemical in your blood that helps create proteins. Vitamin B12, vitamin B6 and vitamin B9 (folate) break …

Androgen inactivates the homocysteine metabolizing enzymes (methionine synthase and betaine-homocysteine methyltransferase) and increases homocysteine levels in mouse granulosa cells.

These include its impact on hormonal signaling pathways like GnRH and prolactin, its role in activating enzymatic processes that affect testosterone synthesis, its modulation of androgen …

Androgen inactivates the homocysteine metabolizing enzymes (methionine synthase and betaine-homocysteine methyltransferase) and increases homocysteine levels in mouse granulosa cells.