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  1. SOX9 - Wikipedia

    Sox9, also known as SRY-Box Transcription Factor 9, is an important gene is sex determination. The SOX family of genes are all transcription factors for the Y chromosomal sex-determining …

  2. SOX9 gene: MedlinePlus Genetics

    The SOX9 gene provides instructions for making a protein that plays a critical role during embryonic development. The SOX9 protein is especially important for development of the …

  3. SOX9 Gene - GeneCards | SOX9 Protein | SOX9 Antibody

    Nov 14, 2025 · Complete information for SOX9 gene (Protein Coding), SRY-Box Transcription Factor 9, including: function, proteins, disorders, pathways, orthologs, and expression.

  4. SOX9 in cartilage development and disease - PMC

    SOX9 is a pivotal transcription factor in chondrocytes, a lineage essential in skeletogenesis. Its mandatory role in transactivating many cartilage-specific genes is well established, whereas a …

  5. Entry - *608160 - SRY-BOX 9; SOX9 - OMIM - (OMIM.ORG)

    SOX9 is a transcription factor essential for both sex and skeletal development. Transient expression of the Y chromosome gene SRY (480000) initiates a cascade of gene interactions …

  6. SOX9: Its Function in Human Development and Disease

    Aug 1, 2025 · SOX9, or SRY-Box Transcription Factor 9, is a primary protein that regulates gene activity within the human body. It belongs to the SOX (SRY-type HMG box) family of …

  7. SOX9: a key transcriptional regulator in organ fibrosis

    Feb 5, 2025 · SOX9 is a member of the SOX (SRY-associated high mobility group box) family of transcription factors. It impacts cell destiny by activating genes responsible for maintaining …

  8. SOX9 - an overview | ScienceDirect Topics

    SOX9 is defined as a transcription factor belonging to the SRY-related HMG box (SOX) family, characterized by a well-conserved HMG box and involved in the regulation of target genes in …

  9. The versatile functions of Sox9 in development, stem cells, and …

    In this review, we confine our discussion to one of the well-characterized SoxE proteins, Sox9. After discussing multiple levels of regulation and mechanisms, we review the versatile …

  10. SOX9 in organogenesis: shared and unique transcriptional …

    Sep 17, 2022 · In this review, we describe common and unique functions of SOX9 among tissues and organs, and the varied mechanisms through which SOX9 acts.