These RNA catalysts may have pharmaceutical applications. For example, a ribozyme has been designed to cleave the RNA of HIV. If such a ribozyme were made by a cell, all incoming virus …

Jan 19, 2026 · Discuss the significance of ribozyme catalysis in the RNA world hypothesis and how modern ribozymes (and engineered artificial ribozymes) inform our understanding of early biocatalysis.

Feb 12, 2026 · Starting from random RNA sequence pools, we discovered a polymerase ribozyme (named QT45, AlphaFold3 prediction shown in cyan), only 45 nt in length. This ribozyme displays a …

In this context, there was much rejoicing when a series of papers over the last few years established that the ribosome, that gigantic particle that was always thought to contain a large RNA framework for …

Nov 25, 2025 · Glucosamine-6-phosphate riboswitch ribozyme (gim ribozyme) The glmS ribozyme is a self-cleaving RNA motif found in the 5′-UTR of the glmS gene in many Gram-positive bacteria, and it …

A ribozyme is an RNA molecule that can cleave phosphodiester bonds independently of protein-based enzymes. It can be delivered in vivo as synthetic oligonucleotides or expressed from transgenes, …

Jun 15, 2025 · A ribozyme is a ribonucleic acid (RNA) molecule that can catalyze a specific biochemical reaction, functioning much like a protein-based enzyme. The discovery of ribozymes in the early …

Jan 10, 2026 · To enable a sensed RNA to activate diverse RNA effectors, the authors engineer a programmable dual-site ribozyme that, upon RNA trigger binding, self-cleaves to release an …

Jul 24, 2023 · A ribozyme is a ribonucleic acid (RNA) enzyme that catalyzes a chemical reaction. The ribozyme catalyses specific reactions in a similar way to that of protein enzymes.

Ribozyme Notes: Explore ribozyme structure and functions: learn how these RNA molecules catalyze reactions, their diverse roles, and their impact on molecular biology.