
Pathology Outlines - Abnormal PT and PTT - causes
Dec 1, 2020 · Coagulation - Abnormal PT and PTT - causesPT and aPTT methods measure time to fibrin clot formation PT and aPTT results are reported in seconds Common causes of prolonged PT …
Pathology Outlines - PT - Prothrombin time
Nov 1, 2012 · Prolonged PT with normal PTT: warfarin or vitamin K deficiency (decreases function of factors II, VII, IX, X, protein C, protein S), liver dysfunction (decreases hepatic synthesis of all …
Pathology Outlines - Vitamin K deficiency / warfarin use
Dec 1, 2023 · Practice answer #1 E. Prolonged prothrombin time (PT). The lack of postnatal vitamin K supplementation and exclusive breastfeeding increases risk of vitamin K deficiency, which usually …
Pathology Outlines - Mixing studies
Aug 6, 2020 · Coagulation - Mixing studiesMixing studies help distinguish clotting time prolongation due to a coagulation factor deficiency or an inhibitor, e.g. lupus anticoagulant To perform a mixing study, …
Pathology Outlines - PT / INR and aPTT
Jan 31, 2022 · Coagulation - PT / INR and aPTT; Prothrombin time (PT) and activated partial thromboplastin time (aPTT) are common initial tests in the evaluation of patients with suspected …
Pathology Outlines - Disseminated intravascular coagulation (DIC)
Jan 4, 2022 · Laboratory Prolonged prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) Elevated D dimers and other fibrin degradation products (but D dimer may be …
Pathology Outlines - Reptilase time
Nov 1, 2012 · Clotting time similar to thrombin time, but uses snake venom (reptilase) instead of thrombin Measure rate of fibrin clot formation after addition of reptilase to citrated plasma Generates …
Pathology Outlines - Antiphospholipid syndrome (APS) testing
Dec 30, 2025 · Ideally, precede antiphospholipid syndrome testing with screening coagulation assays: prothrombin time (PT), activated partial thromboplastin time (aPTT), thrombin time Laboratory …
Cardiac (congestive) hepatopathy and Fontan associated liver disease
Jun 5, 2023 · Prolonged prothrombin time / international normalized ratio (PT / INR) Ascitic fluid may show high serum to ascites albumin concentration gradient (JAMA 2016;316:340) Gradients ≥ 1.1 …
Pathology Outlines - Hereditary bleeding disorders - general
Jan 7, 2025 · Answer D is incorrect because prolonged prothrombin time or activated partial thromboplastin time are often seen in secondary hemostasis disorders. Comment Here Reference: …