Feb 19, 2025 · This section outlines the complete paraffin embedding workflow, from fixation to block formation, ensuring optimal results for histological and molecular analyses.

Paraffin embedding is a standard technique used in clinical and research laboratories to create a formalin-fixed, paraffin-embedded (FFPE) block of tissue. Formalin-fixed tissue undergoes …

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Apr 9, 2024 · Formalin-Fixed Paraffin-Embedded (FFPE) tissue is a widely used method for preserving tissues in histopathology. Despite its challenges, such as protein cross-linking and …

Parablocks, preformed paraffin blocks, are specifically shaped to fit easily into your ASP or PELORIS tissue processors. No measuring or topping off needed. Additional infiltration & …

Jul 30, 2025 · As the wax cools and solidifies, it forms a solid paraffin block with the tissue embedded within it. This block provides mechanical support, allowing thin sections to be cut.

Technical Note INTRODUCTION This document provides a guide for preparing paraffin embedded blocks from fixed tissue specimens and producing sections or scrolls for …

This is routinely achieved by placing the paraffin blocks on ice, cooling both the tissue and the wax to a similar consistency and swelling the tissue to make it easier to section.

3.4.1 Preparing the Paraplast Block: 1. Remove excess Paraplast from the stainless-steel mold using a razor blade, exposing the tissue surrounded by Paraplast.

Dec 5, 2023 · Immediately prior to embedding, spray wax mold with "Mold Grease" and coat the bottom layer of the mold with melted paraffin. Take your sample and orient it on top of the …

Embedding tissue into paraffin blocks supports the tissue structure and enables very thin sections to be cut and mounted onto microscope slides for analysis. This protocol describes how to cut …

Aug 4, 2025 · Paraffin embedding is a crucial step in preparing biological tissues for microscopic examination. This process involves infiltrating tissue samples with paraffin wax to provide …

Oct 21, 2025 · A paraffin block cabinet, also referred to as a paraffin block storage cabinet or tissue block storage cabinet, represents a specialized storage system engineered specifically …

Oct 20, 2020 · Paraffin is the most frequently used embedding medium for histological examination of tissue sections. This chapter presents the composition of paraffin, the role of …

Feb 10, 2025 · Paraffin embedding is one of the most widely used techniques in histopathology. This method is employed to preserve tissue samples for microscopic examination and study.

Jul 29, 2025 · This technique involves preserving biological samples within a block of paraffin wax, which stabilizes the tissue and maintains its structural integrity, allowing for detailed …

Section paraffin blocks at the desired thickness (usually 4-5 µm) on a microtome and float on a 40°C water bath containing distilled water. Transfer the sections onto a Superfrost Plus slide. …

Parablocks, preformed paraffin blocks, are specifically shaped to fit easily into your ASP or PELORIS tissue processors. No measuring or topping off needed. Additional infiltration & …

Aug 1, 2025 · Paraffin blocks are solid blocks of wax used to embed tissue samples. This process allows for the creation of thin sections, crucial for microscopic examination. These blocks …

Jun 26, 2025 · When a patient has a biopsy or a tumor removed, the tissue is processed into paraffin blocks. Pathologists examine stained sections from these blocks to identify cellular …