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  1. Janus kinase inhibitor - Wikipedia

    Janus kinase inhibitor ... A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family …

  2. What are JAK inhibitors and how do they work? - Drugs.com

    Jul 15, 2025 · Janus kinase (JAK) inhibitors are a group of medicines that help block immune system signals in the body that can lead to swelling (inflammation) and pain in conditions like rheumatoid …

  3. JAK Inhibitors: Uses, Types, Side Effects, and More

    Aug 23, 2025 · In this article, learn about the dosage, uses, and ongoing research underway for JAK inhibitors available in the United States, as well as common side effects, contraindications, and …

  4. JAK Inhibitors 101 - The Rheumatologist

    Jul 28, 2025 · The JAK-signal transducer and activator of transcription (STAT) pathway is central to immune dysregulation in many autoimmune diseases due to its role in transducing signals from an …

  5. JAK inhibitors: an evidence-based choice of the most ...

    Recently, Janus kinase inhibitors (JAKi) have been developed to block the effect of proinflammatory cytokines in IMIDs.

  6. List of the 9 Leading JAK Inhibitor Drugs - GoodRx

    Aug 13, 2024 · Janus kinase (JAK) inhibitors are a group of medications with many uses. Rinvoq (upadacitinib), Xeljanz (tofacitinib), and Cibinqo (abrocitinib) are options for eczema and other …

  7. JAK inhibitor selectivity: new opportunities, better drugs?

    Sep 9, 2024 · In this update, we discuss the background of JAK inhibitors, current approved indications and adverse effects, along with new developments in this field.