This DNAzyme cleaves complementary RNAs efficiently in a sequence specific manner between an unpaired purine and a paired pyrimidine. DNAzymes targeting AU or GU vs. GC or AC are …

Deoxyribozymes or DNAzymes are single-stranded catalytic DNA molecules that are obtained by combinatorial in vitro selection methods.

Jun 17, 2024 · High-precision DNA-based biocatalysts, known as DNA enzymes or DNAzymes, are experiencing a revival in biotechnological, analytical, and therapeutical applications.

DNAzymes -- a word made up of DNA and enzyme -- are catalytically active DNA sequences. They comprise a catalytic core comprising around 15 nucleic acids flanked by short binding …

DNAzymes, deoxyribozymes, or simply DNA enzymes, are single-stranded DNA molecules that, like proteins and ribozymes, possess the ability to adopt complex 3D folds in order to perform …

4 days ago · Results and discussion Identification of the minimal Zn 2+ -dependent DNAzyme, minGAA We set up an in vitro screening scheme to obtain nucleic acid enzymes, modeled …

Timeline summary of important events in the development of DNAzyme based biosensors. This article will be exclusively dedicated to reviewing the design and applications of DNAzyme …

Mar 30, 2021 · A typical DNAzyme is a short single-stranded DNA molecule comprising a catalytic core flanked on each side by a target-recognition arm (Fig. 1a).

Sep 4, 2019 · We will begin with a description of the in vitro selection method with which an RNA-cleaving DNAzyme can be derived. This will be followed by a discussion on a few well-studied …

DNAzyme, also known as deoxyribozyme or catalytic DNA, is a class of enzymes whose chemical essence is short single-stranded DNA. Its special DNA sequence allows it to fold into a …