Figure 1: Dynamics of tRNA modifications as BCG enter and exit hypoxic non-replicating persistence. Figure 3: The choice between codons Thr ACG and Thr ACC influences protein up- or downregulation in ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
During translation, the ribosome progressively coordinates the dynamic interplay of tRNA and protein factors to decipher individual codons of an mRNA molecule and synthesize protein. The ribosome ...
tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...
When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare form ...