Comparison of PREMM5 and PREMMplus Risk Assessment Models to Identify Lynch Syndrome Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house ...
The study of cancer genomics has revealed that both inherited (germline) and acquired (somatic) genetic variations significantly influence cancer ...
Scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new ...
Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...
Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...
From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...
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