DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...
Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...
As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...
A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...
Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...
A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...
The tiny little powerhouses of our cells: mitochondria, are unique among organelles because they carry their own tiny little genomes. This genetic material is separate from the rest of our genomic DNA ...
Tardigrades, often called water bears or moss piglets, are microscopic creatures that can survive just about anything: boiling heat, freezing cold and crushing pressure. 2 In fact, tardigrades are the ...