Proteins are like Spider-Man in the multiverse. The underlying story is the same: each building block of a protein is based on a three-letter DNA code. However, change one letter, and the same protein ...

The topographical features of DNA in the body may dictate where and when cancer-causing mutations appear in its code. When you purchase through links on our site, we may earn an affiliate commission.

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because ...

Scientists say they have found a pattern of so-called epigenetic 'marks' in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a ...

Tumors with mutations in the BRCA2 cancer-predisposition gene respond better to checkpoint blockade immunotherapy than tumors with mutations in BRCA1, scientists have found. Treatments that harness ...

Studying the genome of thale cress, a small flowering weed, led to a new understanding about DNA mutations. (Pádraic Flood) A simple roadside weed may hold the key to understanding and predicting DNA ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

The ability of a gene to keep functioning despite mutations shows a surprising link to fundamental math. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it ...