Biomedical engineers have grown muscles in a lab to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B ...
DECEMBER 3, 2025—(BRONX, NY)—Two related studies published today in Nature Metabolism show that a specialized intracellular recycling mechanism—chaperone-mediated autophagy (CMA)—is essential for ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...