Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening ...

A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

Researchers have just revealed that a protein called MCL1, already known to help cancer cells avoid death, also orchestrates ...

Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...

A new study reveals how a single cancer protein may simultaneously drive tumor survival and metabolic control, uncovering a hidden link between two core features of cancer. Scientists have uncovered a ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...

The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).

A research team at the Medical University of Vienna has discovered a new approach to treating a particularly frequent and ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...