Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational chemistry, is not unlike using the Rosetta Stone to unlock the secrets of ancient ...

Michael Martynowycz, PhD, assistant professor of structural biology at the Jacobs School of Medicine and Biomedical Sciences, recently described a new technique for solving protein structures in a rec ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a protein and alter its function. A team at HZB has now investigated the Nsp1 ...

Alzheimer's disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer's Association. Current tests often measure the levels of two proteins-amyloid beta (Aβ) and ...

Researchers combined AI simulations with NMR data to capture fleeting structures of intrinsically disordered proteins, offering new insight into protein misfolding linked to neurodegenerative diseases ...

In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.

Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The proteins that give plants their shape and structure are also involved in ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

A new study suggests Alzheimer’s disease may be detectable through subtle shape changes in proteins found in the blood.