Rheumatology Advisor

Setrusumab Misses Primary Endpoint in Osteogenesis Imperfecta Studies

Topline data were announced from two phase 3 studies evaluating setrusumab in patients with osteogenesis imperfecta.
Monthly Prescribing Reference

Benralizumab Misses Primary Endpoint in COPD Trial

While treatment with benralizumab showed numerical improvement over placebo for the primary endpoint, the result was not statistically significant. A phase 3 trial evaluating benralizumab for the ...

PDS Biotech Announces FDA Alignment on use of Progression Free Survival (PFS) as Primary Endpoint

Detailed price information for Pds Biotechnology Corp (PDSB-Q) from The Globe and Mail including charting and trades.
Healio

Novel small molecule for ALS fails to meet primary endpoint in phase 2/3 study

Please provide your email address to receive an email when new articles are posted on . Topline results from a phase 2/3 clinical trial showed that an eIF2B agonist to treat ALS failed to meet its ...
Seeking Alpha

Telitacicept Achieved Primary Endpoint in Phase 3 Clinical Study for Primary Sjögren's Disease with Telitacicept, a Dual BAFF/APRIL Inhibitor

CAMBRIDGE, Mass., Aug. 13, 2025 (GLOBE NEWSWIRE) -- Vor Bio (Nasdaq: VOR), a clinical-stage biotechnology company transforming the treatment of autoimmune diseases ...
Healio

Study: Ellipsoid zone a clinically relevant endpoint in AMD, GA trials

A study supported the ellipsoid zone loss as a meaningful biomarker that can be used to guide clinical trial design in ...
Nasdaq

Press Release: Itepekimab met the primary endpoint in one of two COPD phase 3 studies

AERIFY-1 study met its primary endpoint of a statistically significant reduction in moderate or severe exacerbations in former smokers regardless of eosinophilic phenotype and provided a clinically ...
Business Insider

Axsome falls after one of two Alzheimer’s trials misses primary endpoint

Axsome Therapeutics (AXSM) announced this morning that while the ACCORD-2 Phase 3 trial achieved the primary endpoint with AXS-05 statistically delayed the time to relapse of agitation in patients ...
Medscape

CONCERTO: Laquinimod for Relapsing-Remitting MS Fails to Meet Primary Endpoint

Topline results from the phase 3 CONCERTO trial show that the oral treatment for relapsing-remitting multiple sclerosis (RRMS) did not meet its primary endpoint, according to an announcement from the ...
Nasdaq

Vertex Pharma’s suzetrigine meets Phase 2 primary endpoint in radiculopathy

Vertex Pharmaceuticals (VRTX) announced results from its Phase 2 study of suzetrigine, an investigational, oral, highly selective NaV1.8 pain signal inhibitor in people with painful lumbosacral ...
Cure Today

Tiragolumab Plus Tecentriq Misses Survival Endpoint for Lung Cancer Subset

The SKYSCRAPER-01 study did not achieve its primary endpoint of overall survival for tiragolumab plus Tecentriq versus Tecentriq alone in PD-L1-high non-small cell lung cancer. The safety profile of ...
Seeking Alpha

Itepekimab Met Primary Endpoint in One of Two Chronic Obstructive Pulmonary Disease (COPD) Phase 3 Trials

AERIFY-1 trial met the primary endpoint of a statistically significant reduction in moderate or severe exacerbations in former smokers regardless of eosinophilic phenotype and provided a clinically ...