Together with researchers from University of Oxford, researchers at Karolinska Institutet have demonstrated that a subclass of stem cells that are dedicated to the production of platelets replenish ...

Immune thrombocytopenia (ITP) is a chronic autoimmune disorder associated with platelet destruction and increased bleeding risk, substantial economic burden, and impairment of health-related quality ...

Results from a phase 2 clinical trial designed and overseen by researchers at Mass General Brigham Cancer Institute show that ...

Thrombocytopenia (low platelet count) is common in people with cirrhosis. Possible causes include an enlarged spleen and decreased platelet production. Severe thrombocytopenia can increase the risk of ...

Let-7 miRNAs enable the identification of immune-skewed imMKCLs. a) Heterogenous responsive activities in imMKCLs were identified with let-7a-5p or let-7g-5p miRNA switches, resulting in let-7 ...

SAN DIEGO -- Treatment with an investigational oral inhibitor of Bruton's tyrosine kinase (BTK) was safe and boosted platelet counts in heavily pretreated patients with immune thrombocytopenia (ITP), ...

Those with an increased risk of bleeding may require platelet transfusion in various medical situations such as after a severe injury or prior to major surgery, to prevent bleeding or excessive blood ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

Representative results of turbulent energy and shear stress for VerMES3, VerMES10, and VerMES50. There exists a defective flow space in the area surrounded by yellow dotted lines. iPS cell-derived ...

PL BioScience, a German life science company specializing in the production and development of human platelet lysate (HPL) for cell expansion, reported the first-time production of an artificial HPL ...