The human brain contains more connections between neurons than there are stars in the Milky Way. Decoding the electrical activity behind all those cells is the massive task that excites neural ...

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Although previous ...

Bipolar disorder: Reading the neural circuit before the clinical storm arrives ...

Netrin1 is a protein that was first characterized for its axon guidance activities during embryonic development. The netrin family has been shown to play many critical roles in developmental and ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...

Protocadherins, a subfamily within the cadherin superfamily, are fundamental to the precise organisation of neural circuits. They contribute to cell adhesion mechanisms that underlie synaptic ...

Cheng Lyu is the winner of the 2025 Eppendorf & Science Prize for Neurobiology for her work in understanding how neural circuits assemble with such remarkable precision during development. Neural ...

A detail of a figure from the paper shows synapses formed between a neuron (above) and muscle (below) a narrow cleft. The distinct T-bar shape indicates an active zone. In the upper image, the synapse ...

The human brain develops through an intricate balance of cellular growth, connectivity, and metabolism. A new study reveals ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a ...