The analysis of the human brain is a central goal of neuroscience. However, for methodological reasons, research has largely focused on model organisms, in particular the mouse. Now, neuroscientists ...

Professor of Pathology, Lee J. Martin, discusses the prevalence and treatment challenges associated with hypoxic-ischemic encephalopathy (HIE) ...

To expand the understanding of memory, a research team has developed a technology called LCD-eGRASP (local circuit dual-eGRASP) that can label synapses of neural circuits within a specific brain ...

Parvalbumin (PV) interneurons act as the brain’s rhythm keepers. By regulating local circuit activity and maintaining excitation–inhibition balance, they help stabilize cortical network function. When ...

Memory, a fundamental tool for our survival, is closely linked with how we encode, recall, and respond to external stimuli. Over the past decade, extensive research has focused on memory-encoding ...

Please provide your email address to receive an email when new articles are posted on . Human GABAergic interneurons were implanted in two patients with drug-refractory focal epilepsy. Preliminary ...

Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epileptic seizures. The researchers say that targeting the ...

Xiaojing Tang et al. at Chongqing Institute for Brain and Intelligence recently published a study in Science Bulletin titled “Parvalbumin Interneurons Are Essential for Tonotopy Strength in the ...

A new study shows how certain genes can lead to brain disorders like autism, epilepsy and schizophrenia. NPR's Jon Hamilton reports that the research also hints at ways to prevent or treat those ...

Labeling of intraregional synapses using LCD-eGRASP in the basolateral amygdala (BLA). Engram cells (Red), Non-engram cells (White), synapses from activated inhibitory interneurons (yellow), and ...