Kanazawa - Proteins must fold in a specific way to function. This is often assisted by molecular chaperones--small proteins whose job is to help others fold to the right shape. Now, Japanese ...

Anthrax toxin has attracted considerable attention in recent years, primarily because of its relevance to the pathogenesis of Bacillus anthracis, a bioterrorism agent. Less widely appreciated is the ...

Researchers have pushed the limits of the Orbitrap mass analyzer, an instrument with relatively high resolution, to collect mass spectra of intact protein complexes with molecular weights approaching ...

The chaperonin proteins GroEL and GroES are cellular nanomachines driven by the hydrolysis of ATP that facilitate the folding of structurally diverse substrate proteins. In response to ligand binding, ...

Scientists have studied molecular interactions in the chaperonin protein GroEL. GroEL is alternately bound and unbound by a co-chaperonin, GroES. Against expectations, the 'football' complex -- where ...