In this phase 2 study, researchers aimed to evaluate the effectiveness of tyrosine kinase inhibition in relapsed or refractory germ cell tumors.

The 2026 GU ASCO annual meeting featured a testicular cancer session and a presentation by Dr. Jennifer King discussing a ...

Can fragments of tumor DNA in the blood predict whether chemotherapy will be effective? Researchers at the Princess Máxima ...

In human cells, DNA carries chemical or "epigenetic" marks that decide how genes will be used in different tissues. Yet in a ...

Based on the NCCN 1.2026 guidelines for the management of CSI seminoma, surveillance is strongly preferred for pT1-pT3 tumors, and the NCCN does not recommend risk-adapted treatment for CSI seminoma ...

Germ cell development and oogenesis represent central processes in the reproduction of invertebrates, exhibiting remarkable diversity in cellular architecture, developmental mechanisms and functional ...

Testicular germ cell tumors are on the rise in the US. The incidence among Hispanic men now surpasses that of non-Hispanic White men, who have historically had the highest incidence. The incidence of ...

Our bodies are constantly under siege by foreign invaders; viruses, bacteria and parasites that want to infiltrate our cells. A new study in the journal eLife sheds light on how germ cells - sperm and ...

A research team at the IPK Leibniz Institute has developed a method that enables the detailed observation of female ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...