No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

When two defective gene variants combine, normal protein function can sometimes be restored.

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Scientists have discovered an interaction between genes that increases the risk of developing a type of alopecia. Scientists have discovered an interaction between genes that increases the risk of ...

Alopecia refers to hair loss and can affect the scalp, eyebrows, eyelashes, and other areas of the body. There are different types of alopecia including androgenetic alopecia, alopecia areata, anagen ...

Alzheimer’s may be driven far more by genetics than previously thought, with one gene playing an outsized role. Researchers ...

Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism. While scientists have long known that certain core circadian clock genes ...

By Dr. Priyom Bose, Ph.D. By analyzing bowel movement frequency in more than 268,000 people, researchers uncover how thiamine-processing genes shape gut motility, link constipation and diarrhea to ...

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental ...