Fatty acid oxidation (FAO) disorders comprise a heterogeneous group of inborn errors of metabolism that impair the mitochondrial capacity to convert fatty acids into energy. These inherited conditions ...

The tumor microenvironment (TME) is a metabolically dynamic niche where cancer cells and immune cells interact to influence tumor progression and immune ...

The role of FAO in cancer. FAO provides three essential substances for tumor metabolism, namely acetyl-CoA, NADPH, and ATP. Genes & Diseases publishes rigorously peer-reviewed and high quality ...

While C13 fatty acid remains elusive in human plasma, new findings reveal its microbial origins, unique metabolic pathways, and potential as a biomarker for understanding how diet and the gut ...

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...

Spicy foods can boost your metabolism, which we’ll dive into in a moment. They’re also associated with a host of other ...

A deep dive into the scientific shift toward multi-target obesity therapeutics and its implications for metabolic health and ...

Schematic summary of the glucose and lipid metabolism in fasting and fed states. Obesity is a multifaceted chronic condition characterized by an excessive accumulation of fat, which significantly ...