The neonatal Fc receptor (FcRn) plays a crucial role in maintaining IgG homeostasis by binding to immunoglobulins in a pH-dependent manner. This receptor not only recycles IgG, thereby extending its ...

Scientists at Ghent University have created a mouse model that incorporates human versions of the receptors that recognize the fragment crystallizable (Fc) region of immunoglobulin G (IgG), one of the ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...

Immunotherapy that blocks microglial Fcγ receptors prevents dopaminergic neuron loss in Parkinson’s disease, revealing a potential new strategy.