A multi-institutional team of researchers led by Case Western Reserve University has identified a pattern of clustered genetic changes that appear to encourage growth of colorectal cancer tumors—a ...

Researchers have unveiled CREsted, a comprehensive software powerhouse. CREsted doesn’t just describe how DNA works; it allows scientists to design entirely new, synthetic enhancers—short DNA ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Conceptual illustration showing how high transcriptional activity driven by super-enhancers can lead to DNA breaks at oncogenes. When these breaks are repaired inaccurately, they can give rise to ...

In a time when what defines gender is being questioned and discussed, a new study reveals that single changes in DNA make ...

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.