Very small embryonic-like stem cells (VSELs) are a rare and intriguing subpopulation of adult stem cells that exhibit molecular signatures reminiscent of embryonic stem cells. Identified in various ...

From the moment an embryo starts to take shape, two-way communication is critical for making sure tissues and organs develop correctly. Two of the first physical structures to form in the embryo are ...

Jennifer Zenker receives funding from NHMRC and Viertel Foundation. Most people have heard of stem cells. They are often described as “miracle” cells –ones that can grow into any other type of cell in ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

Senescence. It’s a beautiful-sounding word whose tones suggest it should be a perfume or an essential oil. But that’s not even close. Senescence is the loss of a cell’s power to divide and grow, thus ...

Welcome to Lab Dish, a First Opinion column on regenerative medicine from Paul Knoepfler. Twenty years ago, the use of human embryonic stem cells in research was among the most fiercely debated topics ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Although embryonic stem cells (ESCs) have been successfully derived from mice and rats, efforts to establish chimeric and germline-competent ESC lines in species beyond rodents have been unsuccessful.

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Researchers have succeeded in generating high-quality feline embryonic stem cells using sperm and eggs from testes and ovaries discarded during sterilization surgery. As different as they may seem, ...