Voltage‐gated calcium channels, particularly the CaV2.1 channels encoded by the CACNA1A gene, are central to cerebellar function and synaptic transmission. Dysfunction in these channels leads to a ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium ...

Calcium is critical for bone health, optimal muscle activity, and other body processes such as blood clotting and heart function. How much calcium you need depends on your age and stage of life. Share ...