Researchers discover a new mechanism controlling the uptake of lipids from digested food. The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive ...
A study published in the journal Protein & Cell details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid ...
A key finding of the study was that, when mitochondria did not function properly, enterocytes showed impaired packaging and transport of lipids in the form of chylomicrons. Chylomicrons are crucial ...
A new tool enables biomedical researchers from around the world to quickly see the connections between lipids and proteins inside cells, thanks to a new initiative led by scientists at Oregon Health & ...
Pictures show small intestinal villi from wild type (top) and enterocyte-specific DARS2 knockout mice (bottom) stained for PLIN2 (yellow), TGN38 (red), E-cadherin (green) and DNA (DAPI, blue). The ...
Scarb2 deficiency is associated with alterations in gut microbiota composition and increased intestinal FXR signaling, leading to impairments in lipid absorption and the renewal of the intestinal ...